Although the disease typically occurs in premenopausal women, cases have been reported in postmenopausal women as well. It is a dense collagenous breast mass with little glandular or vascular tissue. Stromal fibrosis is a histopathological finding categorized as fibrocystic change. These changes may occur in about 50% of all women. The patient was scheduled for yearly mammograms to monitor for changes and was told to return if she noticed any changes or symptoms in the mass.įibrocystic change of the breast is a common condition that many women may develop during their lifetime. Thus, she was counseled on the benign nature of the mass and no requirement for surgical follow-up. The patient’s histological findings consistent with stromal fibrosis and fibroadenomatous changes were concordant with the benign features on imaging. The image findings on mammogram and ultrasound exhibited benign characteristics. Subsequent biopsy of the mass demonstrated histopathological evidence of stromal fibrosis with fibroadenomatous changes. The finding was given a BI-RADS score of 4A and the patient was recommended to undergo ultrasound-guided core needle biopsy (Figures (Figures4, 4, ,5). Ultrasound of the axilla demonstrated morphologically normal lymph nodes. Ultrasound of the right breast showed an isoechoic oval mass with circumscribed margins measuring 51 × 13 × 47 mm at the site of the mammographic mass in the subareolar region (Figure (Figure3). The finding was given a BI-RADS score of 0 and the patient was recommended to undergo ultrasound evaluation of the mass. The mammogram indicated a 50 mm circumscribed mass in the retroareolar region of the right breast with no evidence of calcifications or other malignant characteristics (Figures (Figures1, 1, ,2). Prior to the mammogram, the patient had no complaints of a breast mass, breast tenderness, or breast discharge. 23, 2021.A 42-year-old female with a past medical history of Hashimoto’s thyroiditis underwent a routine screening mammogram. In: The Breast: Comprehensive Management of Benign and Malignant Diseases. Etiology and management of benign breast disease. Understanding breast changes: A health guide for women.Fibrosis and simple cysts in the breast.Clinical manifestations and diagnosis of a palpable breast mass. Having fibrocystic breasts doesn't increase your risk of breast cancer. Overgrowth of cells (hyperplasia) lining the milk ducts or milk-producing tissues (lobules) of the breast.A prominence of scar-like fibrous tissue (fibrosis).Fluid-filled round or oval sacs (cysts).When examined under a microscope, fibrocystic breast tissue includes distinct components such as: Fibrocystic breast changes tend to be more bothersome before your menstrual period and ease up after your period begins. The exact cause of fibrocystic breast changes isn't known, but experts suspect that reproductive hormones - especially estrogen - play a role.įluctuating hormone levels during the menstrual cycle can cause breast discomfort and areas of lumpy breast tissue that feel tender, sore and swollen. Small tubes (ducts) conduct the milk to a reservoir that lies just beneath your nipple. The lobes are further divided into smaller lobules that produce milk for breastfeeding. Your doctor evaluated a breast lump but now it seems to be bigger or otherwise changedĮach breast contains 15 to 20 lobes of glandular tissue, arranged like the petals of a daisy.Breast changes persist after your period.You have specific areas of continuous or worsening breast pain.You find a new or persistent breast lump or area of prominent thickening or firmness of the breast tissue.However, make an appointment with your doctor if: Most fibrocystic breast changes are normal. These changes happen rarely after menopause unless you're taking hormone replacement medicine such as estrogen or progesterone. Monthly increase in breast pain or lumpiness from midcycle (ovulation) to just before your period and then gets better once your period startsįibrocystic breast changes occur most often between 30 and 50 years of age.Breast changes that are similar in both breasts.Green or dark brown nonbloody nipple discharge that tends to leak without pressure or squeezing.Breast nodules or lumpy tissue change in size with the menstrual cycle.Generalized breast pain or tenderness or discomfort that involves the upper outer part of the breast.Breast lumps or areas of thickening that tend to blend into the surrounding breast tissue.Signs and symptoms of fibrocystic breasts may include:
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